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產品名稱: Recombinant Human GGF2
產品型號: Z101659
產品展商: 其他品牌
產品文檔: 無相關文檔
簡單介紹
Recombinant Human GGF2
Recombinant Human GGF2
的詳細介紹
|
Print Version |
| Alternative Names |
GGF2, Pro-neuregulin-1, membrane-bound isoform, Acetylcholine receptor-inducing activity, ARIA, Breast cancer cell differentiation factor p45, Glial growth factor, Heregulin, HRG, Neu differentiation factor, Sensory and motor neuron-derived factor
Recombinant Human Glial Growth Factor (GGF2) |
| Description |
Neuregulins (NDF, heregulin, GGF ARIA, or SMDF) are EGF-like growth and differentiation factors that signal through tyrosine kinase receptors of the ErbB family. The ErbB2 and ErbB4 receptors cooperate in transmission of neuregulin-1 signals in the heart, whereas ErbB2 and ErbB3 cooperate in neural crest cells. |
| Gene Symbol |
GGF2 |
| Gene ID |
3084 |
| Accession No. |
Q02297 |
| Source |
E. coli |
| Appearance |
Lyophilized Powder |
| Molecular Weight |
34.0 kDa |
| Endotoxin Level |
<1.0 EU/μg of recombinant protein as determined by the LAL method. |
| Purity |
>95% as determined by SDS-PAGE |
| Bioactivity |
The ED(50) was determined by the dose-dependent phosphorylation of human MCF-7 cells was found to be < 20 ng/mL, corresponding to a specific activity of 5.0 x 10^4 Units/mg. |
| Formulation |
Recombinant GGF2 was lyophilized from a 0.2 μm filtered 0.02M PB, pH 7.0. |
| Reconstitution |
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
| Storage |
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
| Usage |
For research use only. Not for diagnostic or therapeutic use. |
