Anti-Platelet Derived Growth Factor Receptor Beta (PDGFR b) Antibody
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產(chǎn)品名稱(chēng): Anti-Platelet Derived Growth Factor Receptor Beta (PDGFR b) Antibody
產(chǎn)品型號(hào): Y105327
產(chǎn)品展商: 其他品牌
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Anti-Platelet Derived Growth Factor Receptor Beta (PDGFR b) Antibody
Anti-Platelet Derived Growth Factor Receptor Beta (PDGFR b) Antibody
的詳細(xì)介紹
| Overview |
Print Version
|
| Product Name |
Anti-Platelet Derived Growth Factor Receptor Beta (PDGFR b) Antibody |
| Description |
Rabbit polyclonal to PDGF Receptor beta.
Platelet-derived growth factor receptors exhibit tyrosine-protein kinase activity and have been implicated in the control of cell proliferation, survival and migration. PDGF receptors, PDGFR-alpha and PDGFR-beta, have 5 extracellular immunoglobulin-like domains and an intracellular tyrosine kinase domain. Upon binding a PDGF, the receptors form homo-and heterodimers. Dimerization of the receptors results in phosphorylation in the complex. More than 10 different SH2-domain-containing molecules have been shown to bind to different autophosphorylation sites in the PDGF-alpha and beta receptors. PDGF alpha receptors are expressed in oligodendrocyte progenitor cells and PDGF beta receptors are expressed on neurons.
|
| Subtype |
polyclonal |
| Raised In |
Rabbit |
| Immunogen |
Synthetic peptide (QPNEGDNDYIIPLA) corresponding to the aa 1013-1025 of
Human PDGF Receptor β containing a carboxy-terminal alanine residue. |
| Guarantee |
abm guarantees that all our Anti-Platelet Derived Growth Factor Receptor Beta (PDGFR b) Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Properties |
|
| Formulation |
Liquid |
| Quantity |
200 μg |
| Clone |
Polyclonal Antibody |
| Storage |
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Purity |
Affinity purified |
| Species Reactivity |
human, mouse |
| Specific References |
|
Y105327 has not yet been referenced specifically in any publications.
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