Anti-Phospho- Epidermal Growth Factor Receptor (EGFR) (TYR1173) Antibody
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產(chǎn)品名稱: Anti-Phospho- Epidermal Growth Factor Receptor (EGFR) (TYR1173) Antibody
產(chǎn)品型號(hào): Y103408
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Anti-Phospho- Epidermal Growth Factor Receptor (EGFR) (TYR1173) Antibody
Anti-Phospho- Epidermal Growth Factor Receptor (EGFR) (TYR1173) Antibody
的詳細(xì)介紹
Overview |
Print Version
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Product Name |
Anti-Phospho- Epidermal Growth Factor Receptor (EGFR) (TYR1173) Antibody |
Description |
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The protein kinase family is one of the largest families of proteins in eukaryotes, classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma. Phospho- Epidermal Growth Factor Receptor (EGFR) (TYR1173) clone number 9H2 |
Subtype |
monoclonal |
Raised In |
mouse |
Immunogen |
KLH - conjugated, sythetic peptide containing the Y1173 motif of the human EGFR. |
Guarantee |
abm guarantees that all our Anti-Phospho- Epidermal Growth Factor Receptor (EGFR) (TYR1173) Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
Properties |
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Formulation |
Liquid |
Quantity |
50 μg |
Clone |
Monoclonal Antibody |
Storage |
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
Storage Buffer |
50μg of mouse monoclonal antibody lyophilized from 1 ml of PBS. 0.09% sodium azide, PEG and sucrose. Rehydrate with 500 μl of sterile distilled water. Final solution is 0.1 mg/ml. |
Purity |
Affinity purified |
Isotype |
IgG1k |
Species Reactivity |
human, mouse |
Anti-Phospho- Epidermal Growth Factor Receptor (EGFR) (TYR1173) Antibody Images |
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Specific References |
Y103408 has not yet been referenced specifically in any publications.
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