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產(chǎn)品名稱: Recombinant Human CXCL11
產(chǎn)品型號: Z100585
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
Recombinant Human CXCL11
Recombinant Human CXCL11
的詳細(xì)介紹
|
Print Version |
| Alternative Names |
CXCL11, C-X-C motif chemokine 11, Beta-R1, H174, Interferon gamma-inducible protein 9, IP-9, Interferon-inducible T-cell alpha chemoattractant, I-TAC, Small-inducible cytokine B11
Recombinant Human IFN-Inducible T-cell Chemoattractant (CXCL11) |
| Description |
The CXCL11 belongs to the CXC chemokine family characterized by the presence of one amino acid in between the two NH2-terminal cysteines. CXCL11 is produced by a variety of cells including leukocytes, fibroblasts, and endothelial cells upon stimulation with interferons (IFNs). Simultaneous stimulation of fibroblasts or endothelial cells with IFN-gamma and Interleukin-1b or the TLR3 ligand double-stranded RNA results in a synergistic increase of CXCL11 production. CXCL11 attracts natural killer cells and activated T-helper 1 cells. Like CXCL9 and CXCL10, CXCL11 signals through CXC chemokine receptor 3 (CXCR3). |
| Gene Symbol |
CXCL11 |
| Gene ID |
6373 |
| Accession No. |
O14625 |
| Source |
E. coli |
| Appearance |
Lyophilized Powder |
| Molecular Weight |
8.0 kDa |
| Endotoxin Level |
<1.0 EU/μg of recombinant protein as determined by the LAL method |
| Purity |
>95% as determined by SDS-PAGE |
| Gel Image |
 |
| Bioactivity |
Determined by its ability to chemoattract human T cells using a concentration range of 2.0-10.0 ng/mL |
| Bioactivity Data |
 |
| Formulation |
Lyophilized from a 0.2 μm filtered solution in PB,100 mM NaCl pH 7.5 |
| Reconstitution |
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
| Storage |
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
| Usage |
For research use only. Not for diagnostic or therapeutic use. |
