5'-Nucleotidase, Ecto (NT5E) Antibody
如果您對(duì)該產(chǎn)品感興趣的話,可以
產(chǎn)品名稱: 5'-Nucleotidase, Ecto (NT5E) Antibody
產(chǎn)品型號(hào): abx016042
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無(wú)相關(guān)文檔
簡(jiǎn)單介紹
5'-Nucleotidase, Ecto (NT5E) Antibody
的詳細(xì)介紹
5'-nucleotidase, ecto (NT5E), also known as CD73 (Cluster of Differentiation 73).Ecto-5-prime-nucleotidase (5-prime-ribonucleotide phosphohydrolase; EC 3.1.3.5) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP.The enzyme consists of a dimer of 2 identical 70-kD subunits bound by a glycosyl phosphatidyl inositol linkage to the external face of the plasma membrane.The enzyme is used as a marker of lymphocyte differentiation.Consequently, a deficiency of NT5 occurs in a variety of immunodeficiency diseases (e.g., see MIM 102700, MIM 300300).Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from ecto-NT5 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate.
| Target |
NT5E |
| Reactivity |
Human, Mouse, Cow |
| Host |
Mouse |
| Clonality |
Monoclonal |
| Tested Applications |
ELISA, IHC |
| Recommended dilutions |
ELISA: 1/10000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Purified recombinant fragment of NT5E expressed in E. coli. |
| Purification |
Unpurified Ascites. |
| Isotype |
IgG1 |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
70 kDa |
| GeneID |
4907
23959
281363
|
| Buffer |
Ascitic fluid containing 0.03% sodium azide. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
