8-Oxoguanine DNA Glycosylase 1 (OGG1) Antibody
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產(chǎn)品名稱: 8-Oxoguanine DNA Glycosylase 1 (OGG1) Antibody
產(chǎn)品型號(hào): abx001848
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無(wú)相關(guān)文檔
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8-Oxoguanine DNA Glycosylase 1 (OGG1) Antibody
8-Oxoguanine DNA Glycosylase 1 (OGG1) Antibody
的詳細(xì)介紹
OGG1 Antibody is a Rabbit Polyclonal antibody against OGG1. This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined.
| Target |
OGG1 |
| Reactivity |
Human, Mouse |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB |
| Recommended dilutions |
WB: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Recombinant protein of human OGG1. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Store at 4 °C. |
| Molecular Weight |
Calculated MW: 22 kDa/36 kDa/38 kDa/39 kDa/40 kDa/45 kDa/47 kDa
Observed MW: 36 kDa |
| Swiss Prot |
O15527
|
| GeneID |
4968
|
| Gene Symbol |
OGG1 |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
