ABL1 / 2 (pY393 / 429) Antibody
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產(chǎn)品名稱: ABL1 / 2 (pY393 / 429) Antibody
產(chǎn)品型號: abx000333
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關文檔
簡單介紹
ABL1 / 2 (pY393 / 429) Antibody
的詳細介紹
ABL1/2 (pY393/429) Antibody is a Rabbit Polyclonal antibody against ABL1/2 (pY393/429). Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.
| Target |
ABL1/2 (pY393/429) |
| Reactivity |
Human, Mouse |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB, IHC, IF/ICC |
| Recommended dilutions |
WB: 1/500 - 1/1000, IHC: 1/50 - 1/100, IF/ICC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding Y393/429 of human ABL1/2. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
Calculated MW: 122 kDa/124 kDa/60 kDa/114-128 kDa
Observed MW: 210 kDa |
| Swiss Prot |
P00519
P42684
|
| GeneID |
25/27
|
| Gene Symbol |
ABL1, ABL2 |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
