Acetylcholinesterase (AchE) Antibody
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產(chǎn)品名稱: Acetylcholinesterase (AchE) Antibody
產(chǎn)品型號: abx025536
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
Acetylcholinesterase (AchE) Antibody
的詳細介紹
Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally. This antibody is supplied as crude ascites.
| Target |
Acetylcholinesterase (AchE) |
| Reactivity |
Human, Hamster |
| Host |
Mouse |
| Clonality |
Monoclonal |
| Tested Applications |
WB |
| Recommended dilutions |
Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Human ACHE. |
| Purification |
Mouse Monoclonal Antibody (Mab) supplied as crude ascites. |
| Isotype |
IgG1 |
| Conjugation |
Unconjugated |
| Specificity |
This ACHE antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 582-610 amino acids from the C-terminal region of human ACHE. |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Swiss Prot |
P22303
|
| Buffer |
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
