CD227 / MUC1 (pY1229) Antibody
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產(chǎn)品名稱: CD227 / MUC1 (pY1229) Antibody
產(chǎn)品型號: abx012178
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
CD227 / MUC1 (pY1229) Antibody
的詳細介紹
Phospho-CD227/MUC1 (Tyr1229) Antibody detects endogenous levels of CD227 and MUC1 only when phosphorylated at Tyrosine 1229. This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. This protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. The protein serves a protective function, binding to pathogens, as well as functioning in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
| Target |
CD227/MUC1 (pY1229) |
| Reactivity |
Human |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB |
| Recommended dilutions |
Optimal dilutions/concentrations should be determined by the end user. |
| Purification |
Purified by affinity chromatography. |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Swiss Prot |
P15941
|
| GeneID |
4582
|
| Gene Symbol |
MUC1 |
| OMIM |
158340
|
| HGNC |
7508 |
| Ensembl |
ENSG00000185499 |
| Buffer |
PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
