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產(chǎn)品名稱: CD64 Antibody (FITC)
產(chǎn)品型號: abx200435
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
CD64 Antibody (FITC)
的詳細介紹
Reacts with an antigen (FcγRI) constitutively expressed on monocytes, macrophages and blood dendritic cells. The antigen expression can be induced on neutrophils and eosinophils by interferon γ and granulocyte colony-stimulation factor. Human CD64 is a high affinity receptor for monomeric human IgG1 and IgG3 which is expressed on macrophages, monocytes, and gamma interferon induced neutrophils. CD64 plays an important role in clearance of immune complexes and in antibody dependent cytoxicity.
| Target |
CD64 |
| Reactivity |
Human, Monkey |
| Host |
Mouse |
| Clonality |
Monoclonal |
| Tested Applications |
FCM |
| Recommended dilutions |
FCM: 20 μl/1 million cells. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Human rheumatoid synovial fluid cells and fibronectin-purified monocytes. |
| Purification |
Affinity Chromatography |
| Form |
Liquid |
| Isotype |
IgG1 |
| Conjugation |
FITC |
| Specificity |
The 10.1 monoclonal antibody reacts with human CD64 (FcRI), a 75 kDa type I transmembrane protein. CD64 is the high affinity receptor for IgG and is involved in antibody-dependent cell-mediated cytotoxicity (ADCC), phagocytosis, and regulation of cytokine production. |
| Storage |
Store in the dark at 2-8 °C. |
| Molecular Weight |
72 kDa |
| Swiss Prot |
P12314
|
| GeneID |
2209
|
| Buffer |
The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium Azide |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 3-5 working days. |
| Note |
This product is for research use only. |
