Cell Division Cycle 25C (CDC25C) Antibody
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產品名稱: Cell Division Cycle 25C (CDC25C) Antibody
產品型號: abx010324
產品展商: 其他品牌
產品文檔: 無相關文檔
簡單介紹
Cell Division Cycle 25C (CDC25C) Antibody
Cell Division Cycle 25C (CDC25C) Antibody
的詳細介紹
A member of the MPI phosphatase family. Activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. Shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. At least four transcript variants for this gene exist. Three splice variant isoforms have been described.
| Target |
CDC25C |
| Reactivity |
Human |
| Host |
Mouse |
| Clonality |
Monoclonal |
| Tested Applications |
ELISA, WB, IHC |
| Recommended dilutions |
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Purified recombinant fragment of human CDC25C expressed in E. Coli. |
| Purification |
Unpurified Ascites. |
| Isotype |
IgG1 |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
58 kDa |
| Swiss Prot |
P30307
|
| GeneID |
995
|
| Gene Symbol |
CDC25C |
| OMIM |
157680
|
| Enzyme Commission Number |
EC 3.1.3.48 |
| HGNC |
1727 |
| Ensembl |
ENSG00000158402 |
| Buffer |
Ascitic fluid containing 0.03% sodium azide. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
