Cell Division Cycle 6 (Cdc6) Antibody
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產(chǎn)品名稱: Cell Division Cycle 6 (Cdc6) Antibody
產(chǎn)品型號: abx000586
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
Cell Division Cycle 6 (Cdc6) Antibody
的詳細介紹
Cdc6 Antibody is a Rabbit Polyclonal antibody against Cdc6. The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.
| Target |
Cdc6 |
| Reactivity |
Human |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB |
| Recommended dilutions |
WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Recombinant fusion protein of human Cdc6. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
Calculated MW: 62 kDa
Observed MW: 60 kDa |
| Swiss Prot |
Q99741
|
| GeneID |
990
|
| Gene Symbol |
CDC6 |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS with 0.02% sodium azide, 50% glycerol, pH 7.3. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
