APC - anti human CD16 - Clone 3G8
如果您對(duì)該產(chǎn)品感興趣的話,可以
產(chǎn)品名稱: APC - anti human CD16 - Clone 3G8
產(chǎn)品型號(hào):
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
APC - anti human CD16 - Clone 3G8
APC - anti human CD16 - Clone 3G8
的詳細(xì)介紹
APC
- anti Human
CD16 - 3G8
-
3G8
-
IgG1
-
FCM
-
APC
-
Please refer to the Certificate of Analysis for the lot-specific concentration.
-
Human polymorphonuclear leukocytes
-
Human
-
The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
-
RUO
-
-
-
Store in the dark at 2-8 °C
View larger
Display all pictures
This antibody reacts with the CD16-antigen. CD16 exists as two distinct isoforms, FcγRIIIA and FcγRIIIB. In humans, FcγRIIIA is expressed as a polypeptide-anchored form on monocytes, macrophages, and lymphocytes such as NK cells. T and B cells do not express this Fc receptor. FcγRIIIB is also detected on neutrophils as a GPI-anchored form. Expression of CD16 on lymphocytes and monocytes is similar in non-human primates. Binding of IgG leads to activation of signal transduction pathways, resulting in antibody-dependent cell-mediated cytotoxicity (ADCC), phagocytosis, cytokine release, and antigen presentation.
-
FCRIII, Fc-gamma receptor IIIb, CD16, FCG3, FCGR3, IGFR7
-
-
50-65 kDa
