FITC - anti mouse CD314 - Clone C7
如果您對(duì)該產(chǎn)品感興趣的話,可以
產(chǎn)品名稱: FITC - anti mouse CD314 - Clone C7
產(chǎn)品型號(hào):
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無(wú)相關(guān)文檔
簡(jiǎn)單介紹
FITC - anti mouse CD314 - Clone C7
FITC - anti mouse CD314 - Clone C7
的詳細(xì)介紹
FITC
- anti Mouse
CD314 - C7
-
C7
-
Armenian Hamster IgG
-
Flow Cytometry
-
FITC
-
0.5 mg/ml
-
Soluble mouse NKG2D
-
Mouse
-
The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
-
RUO
-
CD314, clone C7, is a mAb intended for RUO in the identification/enumeration of lymph that express CD314. This reagent is effective for direct IF staining of mouse sample for FCM analysis using ≤1 μg/106 cells.
-
Liquid
-
Store in the dark at 2-8 °C
View larger
CD314 is a lectin-like type II transmembrane protein also known as CD314. It is expressed on NK cells, a subset of CD8+ T cells, ?/? T cells and NK1.1+ T cells, as well as in vitro induced LAK cells. NKG2D serves as a stimulatory immunoreceptor to activate NK cells via the non-covalently associated DAP10 or DAP12 adaptor. Several molecules have been identified as the ligands for NKG2D, including minor histocompatibility molecule, H60, UL16-binding protein-like transcript 1 (Mult1, and a family of retinoic acid early transcript 1 (Rae1) in mice, MHC class-I chain-related protein A (MICA), MICB, and UL16-binding proteins (ULBPs) in humans. present in both mice and humans. NKG2D ligands trigger cytokine (IFN-?, GM-CSF, TNF-?, MIP1? and others) and granzyme release from NK cells. The C7 antibody has been reported to block NK cell killing of targets expressing NKG2D ligands and induce redirected lysis.
-
CD314
-
27007
-
27 kD
