PE - anti mouse CD314 - Clone C7
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產(chǎn)品名稱: PE - anti mouse CD314 - Clone C7
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PE - anti mouse CD314 - Clone C7
PE - anti mouse CD314 - Clone C7
的詳細(xì)介紹
PE
- anti Mouse
CD314 - C7
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C7
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Armenian Hamster IgG
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Flow Cytometry
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PE
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0.2 mg/ml
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Soluble mouse NKG2D
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Mouse
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The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
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RUO
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CD314, clone C7, is a mAb intended for RUO in the identification/enumeration of lymph that express CD314. This reagent is effective for direct IF staining of mouse sample for FCM analysis using ≤1 μg/106 cells.
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Liquid
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Store in the dark at 2-8 °C
CD314is a lectin-like type II transmembrane protein also known as CD314. It is expressed on NK cells, a subset of CD8+ T cells, ?/? T cells and NK1.1+ T cells, as well as in vitro induced LAK cells. NKG2D serves as a stimulatory immunoreceptor to activate NK cells via the non-covalently associated DAP10 or DAP12 adaptor. Several molecules have been identified as the ligands for NKG2D, including minor histocompatibility molecule, H60, UL16-binding protein-like transcript 1 (Mult1, and a family of retinoic acid early transcript 1 (Rae1) in mice, MHC class-I chain-related protein A (MICA), MICB, and UL16-binding proteins (ULBPs) in humans. present in both mice and humans. NKG2D ligands trigger cytokine (IFN-?, GM-CSF, TNF-?, MIP1? and others) and granzyme release from NK cells. The C7 antibody has been reported to block NK cell killing of targets expressing NKG2D ligands and induce redirected lysis.
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CD314
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27007
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27 kD
