gp55, HLA-2, L3 / T4, Ly-4, T cell antigen T4/LEU3, T4, sCD4.
CD4, a single chain transmembrane glycoprotein, is found on a T cell subset (helper/inducer) representing 45% of peripheral blood lymphocytes. It is also present on 80% of thymocytes and at a lower level on monocytes. It is involved in recognition of antigen presented along with MHC class II by APCs. It serves as receptor for HIV.
Antibody to CD4 recognizes T-helper cells required for recognition of class II antigens. It reacts with ~60% of peripheral blood E rosette-positive (E+) cells while showing negligible reactivity with E- cells, monocytes, granulocytes, EBV-transformed B cell lines, and mouse splenocytes.
CD-4 Human Recombinant encoding amino acids 26-226, shows a 48kDa band on SDS-PAGE.
CD4 is fused to a GST tag at N-terminus and purified by standard chromatography techniques.
Escherichia Coli.
Sterile filtered liquid.
Recombinant Human protein at 100μg/ml in 50mM Tris-HCl, (pH-7.5) and 10mM L-glutathione.
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