T-cell growth factor (TCGF), Aldesleukin, Lymphokine, IL-2.

Rat Anti Mouse Monoclonal.

IL2 is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.

NYRmIL-2.

r.Murine IL-2.

Rat IgG2a.

Ion exchange.

1mg/ml in PBS (after reconstitution).

Antibody is shipped lyophilized at ambient temperature.

In lyophilized form, for long periods, store at 4oC in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20oC.

Reconstitute with sterile H₂0. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.

Not tested by ELISA. 1:1,000 dilution will block T cell proliferation induced by specific Ag or concanavaline A.

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