For Research Use Only. Not for use in diagnostic procedures.

A murine monoclonal antibody to an epitope on C5.

This monoclonal antibody was raised against purified human C. It is specific for an antigen expressed on the C5 but not on MAC Complex. This antibody inhibits the lysis of EA and will not bind to MAC bound to a membrane.

Quidel's C5 monoclonal antibody has been used in a variety of experimental techniques including EIA, Western Blot, and RIA. 

References

Sandoval, A., Rong A., et al. Distal recognition site for classical pathway convertase located in the C345C/Netrin module of complement component C5, J. Immunol 165:2 1066-1073., 2000.

Barbashov, S. Wang, C., Nicholson-Weller, A. Serum amyloid P component forms a stable complex with human C5b-6, J. Immunol. 158:3830-3835, 1997.